Disease: Multiple congenital anomalies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZMYND11 Q15326 zinc finger MYND-type containing 11 1.00 0.647 0.500
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
ZC4H2 Q9NQZ6 zinc finger C4H2-type containing 0.91 0.561 0.731
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
VRK1 Q99986 VRK serine/threonine kinase 1 Kinase 2.1E-03 0.621 0.615
TWIST2 Q8WVJ9 twist family bHLH transcription factor 2 Transcription factor 0.56 0.518 0.731
TTN-AS1 TTN antisense RNA 1 0.599 0.577
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SOX2-OT SOX2 overlapping transcript 0.597 0.615
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SATB2 Q9UPW6 SATB homeobox 2 Transcription factor 1.00 0.503 0.769
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
RBPJ Q06330 recombination signal binding protein for immunoglobulin kappa J region Nucleic acid binding 1.00 0.518 0.808
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
RAB23 Q9ULC3 RAB23, member RAS oncogene family 5.6E-03 0.541 0.654
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PPM1D O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 2.2E-11 0.513 0.808
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808